How does acute kidney injury affect serum phosphate levels?

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Multiple Choice

How does acute kidney injury affect serum phosphate levels?

Explanation:
Acute kidney injury reduces the kidneys’ ability to filter and excrete phosphate. Since phosphate is normally cleared through the urine, a sudden drop in GFR and possible tubular dysfunction in AKI leads to phosphate retention and higher serum phosphate levels. Phosphate binding to albumin isn’t a major factor in determining serum phosphate, so the idea that it binds to albumin is not correct.

Acute kidney injury reduces the kidneys’ ability to filter and excrete phosphate. Since phosphate is normally cleared through the urine, a sudden drop in GFR and possible tubular dysfunction in AKI leads to phosphate retention and higher serum phosphate levels. Phosphate binding to albumin isn’t a major factor in determining serum phosphate, so the idea that it binds to albumin is not correct.

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