In which part of the intestine is vitamin B12 absorbed?

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Multiple Choice

In which part of the intestine is vitamin B12 absorbed?

Explanation:
Vitamin B12 absorption relies on a specialized step that occurs in the terminal ileum. After B12 is freed from dietary proteins and binds intrinsic factor in the stomach, the IF–B12 complex travels to the distal small intestine. In the terminal ileum, specific receptors on the enterocytes bind the complex and mediate its uptake, a process that also requires calcium. If the terminal ileum is damaged or removed, B12 absorption is markedly impaired, leading to deficiency. The duodenum and jejunum absorb most other nutrients, while the cecum is part of the large intestine, not the site for B12 uptake.

Vitamin B12 absorption relies on a specialized step that occurs in the terminal ileum. After B12 is freed from dietary proteins and binds intrinsic factor in the stomach, the IF–B12 complex travels to the distal small intestine. In the terminal ileum, specific receptors on the enterocytes bind the complex and mediate its uptake, a process that also requires calcium. If the terminal ileum is damaged or removed, B12 absorption is markedly impaired, leading to deficiency. The duodenum and jejunum absorb most other nutrients, while the cecum is part of the large intestine, not the site for B12 uptake.

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