Is it acceptable to crush enteric-coated tablets for tube feeding?

• A. Yes
• B. No
• C. Only with physician approval
• D. Only if the tablet is very old

Answer: (B)

Enteric-coated tablets are designed to resist stomach acid and release the drug in the small intestine. Crushing them destroys this coating, causing the drug to release in the stomach, which can reduce effectiveness and increase the risk of gastric irritation. It can also create particulates that may clog a feeding tube. For tube feeding, do not crush enteric-coated tablets. If a medication must be given via tube, consult a pharmacist to use an appropriate alternative formulation, such as a liquid form or a non-enteric-coated version.