What is the MAXIMUM parenteral dextrose infusion rate for a term infant?

• A. 4-8 mg/kg/min
• B. 8-12 mg/kg/min
• C. 14-18 mg/kg/min
• D. 18-22 mg/kg/min

Answer: (C)

Dextrose delivery in parenteral nutrition for a term infant is limited to a safe upper range to provide energy without overwhelming the infant’s glucose-handling capacity. In term neonates, the maximum practical rate is about 14–18 mg/kg per minute. This level supplies enough carbohydrate calories to meet metabolic needs while minimizing the risk of hyperglycemia, which can cause dehydration, electrolyte disturbances, osmotic diuresis, and fatty liver. If more calories are needed, they should come from lipids and amino acids rather than pushing glucose higher, because lipids provide a substantial energy source with a lower impact on blood glucose. In short, 14–18 mg/kg/min represents the upper limit at which term infants can safely receive parenteral dextrose without undue metabolic risk.