What is the purpose of pancreatic enzyme therapy?

• A. Pancreatic enzymes reduce gastric emptying
• B. Pancreatic enzymes treat dehydration
• C. Pancreatic enzymes increase appetite
• D. Pancreatic enzymes are used to increase nutrient absorption and decrease steatorrhea

Answer: (D)

Pancreatic enzyme therapy is used to replace insufficient pancreatic enzymes in exocrine pancreatic insufficiency, so digestion can proceed properly in the small intestine. The goal is to restore digestion and absorption of nutrients, especially fats, by providing lipase, amylase, and protease. When these enzymes are lacking, fat digestion is poor, leading to steatorrhea (fatty, bulky stools) and poor nutrient absorption; adding enzymes with meals helps fats, and other nutrients, be digested and absorbed, improving stool form and nutritional status. Enzyme products are usually enteric-coated to survive stomach acid and should be taken with meals or snacks to align with digestive flow and maximize absorption; dosing is adjusted based on fat content and patient response. This therapy does not reduce gastric emptying, treat dehydration, or increase appetite.