What is the volume of IVFE used in the PN example?

• A. 100 mL
• B. 125 mL
• C. 225 mL
• D. 250 mL

Answer: (C)

Translating the prescribed fat dose into the IV fat emulsion volume relies on the fat concentration of the IVFE product. For a typical 10% IVFE, there is about 1 gram of fat in every 10 mL. To deliver a daily fat dose of 22.5 g, you would administer 225 mL of a 10% IVFE (22.5 g × 10 mL/g = 225 mL). This matches the PN example. Always verify the product labeling, because using a different fat concentration (for example, 20%: 2 g per 10 mL) would change the required volume. Also keep in mind the total lipid dose limits when planning the PN.