Which of the following is a contributor to frailty?

• A. Chronic disease
• B. High protein diet
• C. Regular exercise
• D. Adequate nutrition

Answer: (A)

Frailty develops when the body's ability to cope with stressors is reduced. Chronic disease drives this by sustaining ongoing inflammation, increasing metabolic and catabolic demands, and often limiting physical activity. That combination promotes loss of muscle mass (sarcopenia), weaker strength, slower gait, fatigue, and weight loss, all hallmark features of frailty. In this context, chronic disease is a key contributor to frailty because it warps energy balance and reserve over time. By contrast, a high protein diet, regular exercise, and adequate nutrition support muscle mass, strength, and energy, helping to prevent frailty rather than contribute to it.