Which of the following sets of laboratory tests is recommended to be monitored weekly in home parenteral nutrition patients until clinically stable?

• A. Serum glucose; Electrolytes; Blood urea nitrogen; Creatinine; Magnesium; Phosphorus
• B. Electrolytes; Magnesium; Phosphorus; Calcium
• C. Creatinine; Magnesium; Phosphorus
• D. Serum glucose; Electrolytes; Blood urea nitrogen; Creatinine

Answer: (A)

Weekly laboratory monitoring in home parenteral nutrition during the early stabilization phase is about catching metabolic shifts quickly as the PN plan is adjusted. Serum glucose is checked because the sugar load in PN can drive hyperglycemia or hypoglycemia, especially when starting or modifying formulas or insulin therapy. Electrolyte panels are essential since PN can alter sodium, potassium, chloride, and bicarbonate balance, affecting fluid status, blood pressure, and cardiac rhythm. Kidney function, reflected by BUN and creatinine, needs regular review to gauge the nitrogen burden from amino acids and to detect any dehydration or renal impairment that would change PN dosing. Magnesium and phosphorus are frequently out of balance in PN patients, influencing energy metabolism, neuromuscular function, and overall stability, so weekly monitoring helps fine-tune supplementation. Taken together, this set provides a comprehensive view of glucose control, electrolyte and mineral balance, and renal function, which are the most critical areas to assess for safe progression toward clinical stability in home parenteral nutrition.