Which unintentional weight loss threshold is listed among frailty hallmarks?

• A. 5 lbs in 6 months
• B. 10 lbs in 1 year
• C. 20 lbs in 2 years
• D. 15 lbs in 1 year

Answer: (B)

Unintentional weight loss is a key frailty hallmark. In the Fried frailty phenotype, a loss of 10 pounds or more in the past year is the standard threshold used to indicate frailty-related weight loss. This cut-point captures a clinically meaningful change that isn’t explained by intentional dieting or short-term fluctuations. The other options don’t match this established criterion for frailty weight loss, either by time frame or by a smaller/larger threshold. So the correct threshold is 10 pounds in 1 year.