Why does cyclosporine lead to hyperkalemia, and what education should be provided to patients?

• A. Direct effect on the renin-angiotensin-aldosterone system and renal potassium excretion; educate on dietary potassium and regular potassium monitoring.
• B. Indirect effect via increased potassium loss in urine; educate to avoid potassium.
• C. It has no impact on potassium homeostasis; no education needed.
• D. It only affects sodium handling; advise no potassium restrictions.

Answer: (A)